Anticancer potential of Moringa peregrina

Document Type : Mini-reviews

Authors

1 Dept.of Pharmacognosy and Medicinal Plants, Faculty of Pharmacy, Zagazig University

2 Egyptian International Pharmaceutical Industries Company (EIPICO)

3 Faculty of Pharmacy - Suez Canal University

4 Dept.of Biochemistry Faculty of Pharmacy - Suez Canal University

Abstract

Cancer is an advanced disease characterized by numerous etiologies and multiple stages evoked by the deregulation in genetic and epigenetic programs via many factors like hormonal perturbation, microbial infections and chemical carcinogenesis. Once cells become cancerous, they still divide forever with none response of sign programmed cell death or senescence. Treatment relies on radiotherapy and chemotherapy that target cells with fast division. These treatments cause numerous side effects on normal cells division. Natural products have con­tinually and historically been studied for promising new leads in pharmaceutical development. Several plant parts are utilized in traditional medi­cine because they are easily available in rural areas and less expensive compared to new synthetic therapeutic drug. Moringa peregrina (M. peregrina), which belongs to the monogenic Moringaceae family, offers these advantages. Moringa trees possess different medicinal and nutritional value. This current review focuses on the chemical and biological properties of M. peregrina as a promising source of anti-cancer agent(s).

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