Curcumin Mimics: An Overview

Document Type : Mini-reviews

Authors

1 Department of Pharmaceutical organic chemistry, faculty of pharmacy, Suez canal University, Ismailia, Egypt

2 Pharmaceutical Organic Chemistry Department, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza, Egypt

3 Pharmaceutical Organic Chemistry, School of Pharmacy, Suez Canal University

Abstract

Curcumin is a natural product which is isolated from curcuma longa, it was used for several centuries as an anti-inflammatory agent in traditional medicine. Curcumin has several activities including anti-inflammatory, antioxidant, antibacterial and anticancer activity. However, bioavailability, stability and selectivity problems associated with curcumin limited their use, that is why a great effort was done to develop curcumin mimics that overcome these problems. In this review, we will illustrate some different biological activities of curcumin mimetics. Curcumin is a natural product which is isolated from curcuma longa, it was used for several centuries as an anti-inflammatory agent in traditional medicine. Curcumin has several activities including anti-inflammatory, antioxidant, antibacterial and anticancer activity. However, bioavailability, stability and selectivity problems associated with curcumin limited their use, that is why a great effort was done to develop curcumin mimics that overcome these problems. In this review, we will illustrate some different biological activities of curcumin mimetics.

Keywords

Records of Pharmaceutical and Biomedical Sciences
Volume 7, Issue 1
Chemistry
January 2023
Pages 189-196

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