Antimicrobial activity of different extracts of Plicosepalus acacia

El-Shafei, Ghadeer; Al-Hazmi, Bodoor; Marghelani, Afnan; Al-Moalem, Dania; Badr, Jihan M.; Moneib, Nayera A.

doi:10.21608/rpbs.2018.5919

Antimicrobial activity of different extracts of Plicosepalus acacia

Document Type : Original Article

Authors

¹ Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia

² Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt

³ Department of Micobiology and Immunology, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt

10.21608/rpbs.2018.5919

Abstract

The antimicrobial activity of different extracts of Plicosepalus acacia was tested against a number of microorganisms using agar diffusion method. The microorganisms used areStaphylococcus aureus, Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa and Candida albicans. Ethyl acetate extract exhibited the highest activity against the tested Gram-positive bacteria (inhibition zones ranged from 24-25 mm) and also towards the fungus Candida albicans (25 mm inhibition zone). All the tested extracts were highly effective against the well-known highly resistant Gram-negative bacteria Pseudomonus aeruginosa, while the highest activity was observed with the chloroform extract (37 mm).

Keywords

Main Subjects