Phytochemical investigation of Salsola kali extract

Alturkistani, Tariq; Bin Afif, Marwan; Alzahrani, Rashed; Alnouno, Reef; Badr, Jihan M.

doi:10.21608/rpbs.2018.5921

Phytochemical investigation of Salsola kali extract

Document Type : Original Article

Authors

¹ Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah 21589, Saudi Arabia

² Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, Ismailia, 41522, Egypt

10.21608/rpbs.2018.5921

Abstract

The present study focuses on biologically guided fractionation of the extract of Salsola kali, aiming to investigate its anti-inflammatory constituents. The total methanol together with petroleum ether, chloroform and ethyl acetate extracts were investigated for anti-inflammatory activity using rat paw edema test. Petroleum ether extract demonstrated the highest activity (60%) relative to the reference indomethacin. Accordingly, the petroleum ether extract was fractionated using different chromatographic techniques to afford finally 4 compounds identified as lupeol, β-sitosterol, ursolic acid and β-sitosterol-3-O-glucoside.

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