Pseudomonas aeruginosa identifcation and MIC assessment from clinical isolates

Document Type : Original Article

Authors

1 Microbiology and Immunology Department, Faculty of Pharmacy Suez Canal University Egypt

2 Microbiology and Immunology Department, Faculty of Pharmacy, Qassim University, KSA

3 Microbiology and Immunology Department, Faculty of Pharmacy, Cairo University, Egypt

4 Clinical Pathology Department, Faculty of Medicine, Suez Canal University, Egypt

Abstract

Pseudomonas aeruginosa is a common and major opportunistic human pathogen, its causes many and dangerous infectious diseases like cystic fbrosis, wounds, burns inflammation, urinary tract infection, other many infections otitis external, nosocomial infection and causes bacteremia. A main problem in P. aeruginosa infection that exhibits a high degree of resistance to a broad spectrum of antibiotics. A total of 147 patients of Pseudomonas aeruginosa were isolated from Ismailia hospitals. The clinical isolates were collected from wound, sputum and urine. Carbapenem sensitivity was performed per Kirby-Bauer disk diffusion method and minimum inhibitory concentration (MIC) was preformed towards meropenem and imipenem resistant isolates by agar dilution methods. Imipenem and meropenem sensitivity result were 91% and 70%. MICs were carried out for carbapenem resistant isolates. Furthermore P. aeruginosa screening should be managed and antibiotic abuse should be monitored.

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