B:Genus Holothuria an imminent source of diverse chemical entities: A review

Document Type : Mini-reviews

Authors

1 Pharmacognosy department, Faculty of pharmacy, Suez Canal University

2 pharmacognosy department ,faculty of pharmacy, suez canal university

3 Faculty of Pharmacy - Suez Canal University

4 pharmacognosy department,faculty of pharmacy,Suez canal university,Ismailia,Egypt.

5 Pharmacognosy department Faculty of pharmacy Suez Canal University

6 Department of Pharmacognosy, Faculty of Pharmacy, Suez Canal University, 41522, Ismailia, Egypt

Abstract

Nature is a valuable source for many medicines in use. About 30 per cent of the world's drugs are either natural products or their biologically active derivatives. Natural products display a wide range of chemical structures that even are unapproachable by highly formulated synthetic principles. Compared to the terrestrial, marine organisms have provided the widest diversity; thirty-four of the thirty-six phyla of life exist. One of the most important diverse families of sea cucumbers is the Holothuriidae family, which exist in oceans and shallow waters as well. This family comprises five genera. Among them, genus Holothuria which is the most predominant one and represented in Egypt by eight species. Phytochemical investigation of sea cucumbers belonging to genus Holothuria has led to the isolation and identification of numerous chemical compounds of different classes. The current review demonstrated that genus Holothuria is a rich source of cerebrosides, saponins, fatty acids, amino acids and phenolics.

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